Helicobacter pylori infection induces duodenitis and superficial duodenal ulcer in mongolian gerbils

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STOMACH Helicobacter pylori infection induces duodenitis and superficial duodenal ulcer in Mongolian gerbils

Background: There is no direct evidence for an animal model of Helicobacter pylori induced duodenal ulcer. Aim: In this study we evaluated the roles of bacterial strain and age of experimental animals in induction of duodenitis and duodenal ulcer in Mongolian gerbils after H pylori infection. Methods: Specific pathogen free Mongolian gerbils were inoculated orally with three bacterial strains (...

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Helicobacter pylori infection induces duodenitis and superficial duodenal ulcer in Mongolian gerbils.

BACKGROUND There is no direct evidence for an animal model of Helicobacter pylori induced duodenal ulcer. AIM In this study we evaluated the roles of bacterial strain and age of experimental animals in induction of duodenitis and duodenal ulcer in Mongolian gerbils after H pylori infection. METHODS Specific pathogen free Mongolian gerbils were inoculated orally with three bacterial strains ...

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Helicobacter pylori infection induces hyperammonaemia in Mongolian gerbils with liver cirrhosis.

BACKGROUND AND AIMS We previously reported the effect of Helicobacter pylori eradication on hyperammonaemia in patients with liver cirrhosis. However, the role of H pylori as a cause of hyperammonaemia is controversial. We developed an animal model with liver cirrhosis and investigated the effect of H pylori infection on hyperammonaemia. MATERIALS AND METHODS Five week old male Mongolian gerb...

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HELICOBACTER PYLORI Helicobacter pylori infection potentiates aspirin induced gastric mucosal injury in Mongolian gerbils

Background: Helicobacter pylori infection and non-steroidal anti-inflammatory drugs are two major causes of gastric ulceration but interactions between H pylori and these drugs in gastric mucosal injury are unclear. Aims: We studied the influence of experimental H pylori infection on gastric mucosal injury induced by aspirin. Subjects: Male Mongolian gerbils free of specific pathogens were used...

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Relationship of gastric metaplasia and age, sex, smoking and Helicobacter pylori infection in patients with duodenal ulcer and duodenitis.

Gastric metaplasia is one of the factors in duodenal ulcer appearance. The aim of this study was to investigate the frequency of gastric metaplasia and its connection with age, sex, cigarette smoking and H. pylori infection. In the study 216 patients were included. There were 98 patients with duodenal ulcer, 60 with duodenitis, and 58 healthy control subjects. There was no statistically signifi...

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ژورنال

عنوان ژورنال: Gastroenterology

سال: 2003

ISSN: 0016-5085

DOI: 10.1016/s0016-5085(03)80254-8